SubtiBank SubtiBank
nadR [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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nadR [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

transcriptional repressor of genes involved in NAD biosynthesis
locus
BSU27890
pI
5.76
mw
19.00 kDa
function
regulation of NAD biosynthesis
product
transcriptional repressor
essential
no
synonyms
yrxA

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.11|Biosynthesis of NAD(P)]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors], [SW|transcription factors and their control]
  • This gene is a member of the following [SW|regulons]

  • [SW|NadR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,850,716 -> 2,851,258

    Expression and Regulation

    Operon

  • ''[protein|search|nifS]-[protein|search|nadR]'' [Pubmed|8444804]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|8444804]
  • Regulation

  • repressed in the presence of nicotinic acid ([protein|search|NadR]) [Pubmed|8444804,16199587]
  • Regulatory mechanism

  • [protein|search|NadR]: transcription repression [Pubmed|8444804,16199587]
  • Labs working on this gene/protein

  • [SW|Alessandra Albertini], University of Pavia, Italy [http://www-1.unipv.it/genbiom/albertini.html homepage]
  • References

  • 18276644,8444804,16199587