SubtiBank SubtiBank
ykkD [Thu Dec 22 2016 09:55:48 GMT+0100 (CET)]
SAVE THE DATE! 21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.

ykkD [Thu Dec 22 2016 09:55:48 GMT+0100 (CET)]

similar to molecular chaperone
locus
BSU13100
pI
8.00
mw
11.00 kDa
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.11|Other exporters]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|membrane proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,376,855 -> 1,377,172

    The protein

    Protein family

  • paired small multidrug resistance protein family ([SW|PSMR family]) [Pubmed|17942072]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [SW|YkkC]-[SW|YkkD] (likely) [Pubmed|17942072]
  • Expression and Regulation

    Operon

  • ''[protein|search|ykkC]-[protein|search|ykkD]'' [Pubmed|10735877]
  • Regulation

  • induced in the presence of guanidine ([SW|ykkC riboswitch]) [Pubmed|27989440]
  • Regulatory mechanism

  • [SW|ykkC riboswitch]: binding of the ligand guanidine causes transcriptional antitermination [Pubmed|27989440]
  • term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of ''ykkC'' [Pubmed|27120414]
  • Biological materials

    Mutant

  • MGNA-A748 (ykkD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/748 NBRP B. subtilis, Japan]
  • References

    Reviews

  • 17942072
  • Original publications

  • 10735877,21317561,27989440,27120414