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rsiW [2017-03-26 17:36:30]
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rsiW [2017-03-26 17:36:30]

anti-SigW
locus
BSU01740
pI
6.65
mw
23.00 kDa
protein length
208 aa Sequence Blast
gene length
624 bp Sequence Blast
function
control of SigW activity
product
anti-SigW
essential
no
synonyms
ybbM

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|SigW regulon]
  • Gene

    Coordinates
    195,426 -> 196,052

    The protein

    Protein family

  • anti-sigma-W factor family (according to Swiss-Prot)
  • Effectors of protein activity

  • degraded by [protein|CB50289535EA537F63BADD459BD11AA7759A6658|RasP] and [protein|EE3B6B52EA19958E2E46A1545747F5209A6AA036|PrsW] under conditions of alkali shock or in the presence of antimicrobial peptides, respectively. This results in the release of [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]
  • Structure

  • [PDB|5WUQ] (the cytoplasmic domain in complex with [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]) [pubmed|28319136]
  • [SW|Localization]

  • membrane (according to Swiss-Prot)
  • Expression and Regulation
    [[this]]

    Biological materials

    Mutant

  • MGNA-B953 (ybbM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1952 NBRP B. subtilis, Japan]
  • Labs working on this gene/protein

  • [SW|Thomas Wiegert], University of Bayreuth, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/Thomas%20Wiegert-Dateien/Thomas%20Wiegert.html Homepage]
  • References

    Reviews==

  • 20836086,22381678
  • Original Publications

  • 17020587,14993308,16816000,18599827,12207695,16899079,15130127,12884008,12076816,19889088,14993308,28319136