skfC

may be involved in spore killing

Locus: BSU_01935

Isoelectric point: 8.00

Molecular weight: 56.00 kDa

Protein length: 496 aa

Gene length: 1491 bp

Function: may be involved in spore killing

Product: unknown

Essential: no

Synonyms: ybcS

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Coping with stress → Toxins, antitoxins and immunity against toxins
• Prophages and mobile genetic elements → Prophages → Prophage 1

Gene

Coordinates: 215,404 216,894

Expression and Regulation

Operons

• Genes: skfA-skfB-skfC-skfE-skfF-skfG-skfH
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • Spo0A: activation, PubMed, in Spo0A regulon
  • AbrB: repression, PubMed, in AbrB regulon
  • PhoP: activation, PubMed, in PhoP regulon

  Regulation

  • expressed under conditions that trigger sporulation (Spo0A) PubMed

  Additional information

  • Northern blotting during during phosphate limitation showed an intense 0.25 kb 'SkfA'-specific transcript, and a weaker 6.5 kb skfA-skfB-skfC-skfE-skfF-skfG-skfH transcript

Biological materials

Mutant

• MGNA-C514 (ybcS::erm), available at the NBRP B. subtilis, Japan
• BKE01935 (skfC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CCAGAACACCAATGATAGAC, downstream forward: _UP4_CTCTAATGATTAGGAGAAGA
• BKK01935 (skfC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CCAGAACACCAATGATAGAC, downstream forward: _UP4_CTCTAATGATTAGGAGAAGA

References

Reviews

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Original Publications

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