SubtiBank SubtiBank
pucG [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

pucG [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

(S)-ureidoglycine-glyoxylate aminotransferase
locus
BSU32520
pI
5.42
mw
45.00 kDa
function
purine utilization
product
(S)-ureidoglycine-glyoxylate aminotransferase
essential
no
synonyms
yurG

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.1|Utilization of nucleotides]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of nucleotides]
  • This gene is a member of the following [SW|regulons]

  • [SW|PucR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,341,166 -> 3,342,416

    The protein

    Catalyzed reaction/ biological activity

  • transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (glyoxylate) to yield oxalurate and glycine [Pubmed|20852637]
  • Protein family

  • class-V pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Structure

  • [PDB|3ISL] [Pubmed|20852637]
  • Expression and Regulation

    Operon

  • ''[protein|search|pucF]-[protein|search|pucG]'' [Pubmed|12029039]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|12029039]
  • Regulation

  • induced in the presence of purine nucleotides (inducer: allantoin) ([protein|search|PucR]) [Pubmed|12029039]
  • Regulatory mechanism

  • [protein|search|PucR]: transcription activation [Pubmed|12029039]
  • References

  • 11344136,20852637,12029039