SubtiBank SubtiBank
yoaA
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yoaA

similar to spermidine/spermine N-acetyltransferase
locus
BSU_18530
pI
5.92
mw
18.89 kDa
protein length
177 aa Sequence Blast
gene length
534 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]
  • Gene

    Coordinates
    2,020,611 2,021,144

    The protein

    Protein family

  • [SW|Acetyltransferase family] (according to UniProt)
  • Paralogous protein(s)

  • [protein|F92B7EC7A00BF295666D68613932D239F92C7347|YkkB], [protein|18FA5EFCD78C74296F9E52A64DA4A9D635944528|YnaD]
  • [SW|Domains]

  • [SW|N-acetyltransferase domain] (aa 10-177) (according to UniProt)
  • Structure

  • [PDB|5WIF] (from Yersinia pestis, 29% identity)
  • Expression and Regulation

    Operons

    genes
    [gene|928CD0278328BB8642F7D560E42C13D74B4F1341|yoxC]-[gene|8C5ECDA04FA75F6FFA8625431AAC6855D8A1DB08|yoxB]-[gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]
    description
    [Pubmed|10482513]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|10482513,15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|10482513,15805528]
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    Biological materials

    Mutant

  • MGNA-A832 (yoaA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/832 NBRP B. subtilis, Japan]
  • GP1248 (''yoaA''::''tet''), available in [SW|Jörg Stülke]'s lab
  • GP1255 (''[gene|17C3F56CE859BCD7A282C144C46CC92D3506ABF6|acuA]''::''kan'' ''[gene|6072A6EF0766F3D1B1616A20CDC36CCDC6CBDA71|yjcK]''::''cat'' ''[gene|18FA5EFCD78C74296F9E52A64DA4A9D635944528|ynaD]''::''spec'' ''[gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]''::''tet''), available in [SW|Jörg Stülke]'s lab
  • BKE18530 ([gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCAACCACTCCCCACGT, downstream forward: _UP4_TGACGGTATTCTCTTGGTCT
  • BKK18530 ([gene|4A8360E50ADBA4CC859A64A72EBC0A07F70A1764|yoaA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCAACCACTCCCCACGT, downstream forward: _UP4_TGACGGTATTCTCTTGGTCT
  • References

  • 10482513,15805528