SubtiBank SubtiBank
gatC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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gatC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

production of glutamyl-tRNA(Gln)
locus
BSU06670
pI
4.00
mw
10.00 kDa
function
translation
product
glutamyl-tRNA(Gln) amidotransferase (subunit C)
essential
yes
ec
6.3.5.7
synonyms
yerL, yedA

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.10|Aminoacyl-tRNA synthetases]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
  • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|essential genes], [SW|phosphoproteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    728,732 -> 729,022

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP L-glutamyl-tRNA(Gln) L-glutamine = ADP phosphate L-glutaminyl-tRNA(Gln) L-glutamate (according to Swiss-Prot)
  • Protein family

  • gatC family (according to Swiss-Prot)
  • Modification

  • phosphorylated on Arg-3 [Pubmed|22517742]
  • Structure

  • [PDB|2DF4] ([protein|search|GatA]-[protein|search|GatB]-[protein|search|GatC] complex from ''Staphylococcus aureus'') [Pubmed|16809541]
  • [SW|Interactions]

  • [protein|search|GatA]-[protein|search|GatB]-[protein|search|GatC]
  • ([protein|search|GatA]-[protein|search|GatB]-[protein|search|GatC])-[protein|search|GltX]-[protein|search|trnS-Gln] (the [SW|transamidosome]) [Pubmed|20882017], see a [http://www.nature.com/nature/journal/v467/n7315/fig_tab/nature09411_F3.html model of the interaction] [Pubmed|20882017]
  • References

  • 9342321,20882017,22517742,16809541