SubtiBank SubtiBank
cotG [Thu May 19 2016 18:54:24 GMT+0200 (CEST)]
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cotG [Thu May 19 2016 18:54:24 GMT+0200 (CEST)]

outer spore coat protein
locus
BSU36070
pI
10.00
mw
23.00 kDa
function
resistance of the spore
product
spore coat protein
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.5|Class V]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.6|Phosphorylation on a Thr residue]
  • [SW|Categories] containing this gene/protein

  • [SW|sporulation proteins], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|GerE regulon], [SW|GerR regulon], [SW|SigE regulon], [SW|SigK regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,717,238 -> 3,717,825

    The protein

    Catalyzed reaction/ biological activity

  • required for the maturation of [SW|CotB] [Pubmed|26953338]
  • Modification

  • phosphorylated on Ser-15, Ser-39, and Thr-147 [Pubmed|25115591]
  • [SW|Localization]

  • outer spore coat, localization depends on [protein|search|CotE] [Pubmed|22171814]
  • [SW|Interactions]

  • [protein|search|CotB]-[protein|search|CotG] [Pubmed|14762006]
  • Expression and Regulation

    Operon

  • ''[protein|search|cotG]'' [Pubmed|7814326]
  • [SW|Sigma factor]

  • [protein|search|SigE] [Pubmed|15383836], [protein|search|SigK] [Pubmed|15699190,7814326]
  • Regulation

  • expressed late during sporulation in the mother cell ([protein|search|SigE], [protein|search|SigK], [protein|search|GerE]) [Pubmed|15383836,15699190,7814326]
  • Regulatory mechanism

  • [protein|search|GerE]: transcription activation [Pubmed|7814326]
  • [protein|search|GerR]: transcription activation [Pubmed|15621419]
  • Additional information

  • the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
  • References

  • 12884008,7814326,9573176,14762006,15699190,15621419,22171814,21984783,15383836,25115591,26953338