SubtiBank SubtiBank
atpG
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atpG

ATP synthase, part of the F1 complex (subunit gamma)
locus
BSU36820
pI
6.64
mw
31.50 kDa
protein length
287 aa Sequence Blast
gene length
864 bp Sequence Blast
function
ATP synthesis
product
ATP synthase (subunit gamma)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.5|ATP synthesis] → [category|SW 2.1.5.1|ATPase]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    3,782,938 3,783,801

    The protein

    Catalyzed reaction/ biological activity

  • ATP synthesis [http://www.youtube.com/watch?v=uOoHKCMAUMc see a video]
  • Protein family

  • ATPase gamma chain family (according to Swiss-Prot)
  • Effectors of protein activity

  • ATPase activity is inhibited upon binding of Mg-ADP to [protein|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|AtpD] [pubmed|30580998]
  • Structure

  • [PDB|4XD7] (from ''Geobacillus kaustophilus'', 69% identity) [Pubmed|26032434]
  • [SW|Localization]

  • membrane, peripheral via theF0 complex
  • Expression and Regulation

    Operons

    genes
    [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI]-[gene|CC1894D90AC17487A286B2909964916825055F93|atpB]-[gene|6CF7F6303425D8A51E1E01BF18823139E4259A8F|atpE]-[gene|87311FEA265AD3F5526C78D631E7E51BBF01F0D6|atpF]-[gene|E956A30D97B2941108880F3AD48620C4DB6E0EBD|atpH]-[gene|E3FADE979CE6AB6315F67812608FCE00CF4E2453|atpA]-[gene|492EEC8068043DA770F5DC1D54799C4366AE9A01|atpG]-[gene|2A566C2CF8F7B86E05EEF4B7A268E8C102070025|atpD]-[gene|A9DA64F8C7A60E8E2B1EDC99BEA1BD7DD0135AA6|atpC]
    description
    [Pubmed|9353933]

    regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]
  • regulation

  • [protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • the mRNA is processed between [gene|8027AD5C3A92FB9B70E42C119FDEC697A64618C4|atpI] and [gene|CC1894D90AC17487A286B2909964916825055F93|atpB] by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y], this requires the [protein|EE52DFA35B935E551871D079A9BE877DB2001A3B|YmcA]-[protein|6C9A092F38739A3759793EF8B496569CD02C2E3F|YlbF]-[protein|EBD15C174A03B7FCDFFE4C5DB5D86E93F1B9CAC4|YaaT] complex [Pubmed|29794222]
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    Biological materials

    Mutant

  • BKE36820 ([gene|492EEC8068043DA770F5DC1D54799C4366AE9A01|atpG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGATTTCACCACCTTTT, downstream forward: _UP4_TAGAAAGATTTTGTCAGGAG
  • BKK36820 ([gene|492EEC8068043DA770F5DC1D54799C4366AE9A01|atpG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36820 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGATTTCACCACCTTTT, downstream forward: _UP4_TAGAAAGATTTTGTCAGGAG
  • References

    Reviews

  • 23356252,23341301,23267178,22822068,21524994,19489730,17208001,16730323
  • Original publications

  • 7961438,26032434,30580998