SAVE THE DATE!
21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.
DNA-dependent ATPase, recombination factor, involved in processing recombination intermediates at replication forks
control of the access of the replication machinery to a collapsed replication fork
DNA-dependent ATPase, recombination factor
categories[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.6|DNA repair/ recombination/ based on similarity]
Phenotypes of a mutantsensitive to H2O2 [pubmed|30954900]
Catalyzed reaction/ biological activityinhibits [protein|AF5ADDA2A98EC18BB72A81AA0336E639C0D1F430|PriA]-dependent initiation of [category|SW 3.1.1|DNA replication] [pubmed|29947798]contributes to error-prone DNA repair, links re-initiation of DNA replication with repair-by-recombination by controlling the access of the replication machinery to a collapsed replication fork [pubmed|30954900]
Protein family[SW|AAA ATPase family] (according to UniProt)
Effectors of protein activityATPase is stimulated by ssDNAdsDNA junctions or dsDNA ends [pubmed|29947798]ssDNA-dependent ATPase is stimulated by [protein|8DE39680CA7663803A107066FBE9AFFCC77DB72A|SsbA] bound to ssDNA [pubmed|29947798]
Structure[PDB|3PVS] (from E. coli, 39% identity) [pubmed|21297161]
additional informationfor the corresponding ''E. coli'' protein, RarA, see [http://ecoliwiki.net/colipedia/index.php/rarA RarA]
Expression and Regulation
view in new tab
MutantMGNA-A827 (yrvN::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/827 NBRP B. subtilis, Japan]BKE27530 ([gene|48BCA38E609E443406E03A32D2BB8DA2E9915A71|rarA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTATCATCTCTCCTTAC, downstream forward: _UP4_TAAAACAAAAAAACAGCCTTBKK27530 ([gene|48BCA38E609E443406E03A32D2BB8DA2E9915A71|rarA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27530 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTATCATCTCTCCTTAC, downstream forward: _UP4_TAAAACAAAAAAACAGCCTT