SubtiBank SubtiBank
fliS
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fliS

chaperone for the export of [protein|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB|flagellin]
locus
BSU_35330
pI
5.23
mw
14.99 kDa
protein length
133 aa Sequence Blast
gene length
402 bp Sequence Blast
function
[category|SW 4.1.1|Motility and chemotaxis]
product
chaperone for [protein|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB|flagellin] export
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins]
  • Gene

    Coordinates
    3,632,488 3,632,889

    The protein

    Catalyzed reaction/ biological activity

  • prevents premature assembly of [protein|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB|Hag] [Pubmed|26490009]
  • Protein family

  • FliS family (single member, according to UniProt)
  • Structure

  • [PDB|1VH6] [Pubmed|16021622]
  • [PDB|6GOW] (complex with flagellin) [Pubmed|30068950]
  • [SW|Localization]

  • cytoplasm (according to UniProt)
  • Expression and Regulation

    Operons

    genes
    [gene|4DBF4635B5C5A7541E8F97440D139DAA02547B99|yvyC]-[gene|C6012DEA301DF5B2DDD7E673A736BD3E5163F209|fliD]-[gene|4882FAD988FEDD0E72E4CAFB10C8DE61DDAC23B0|fliS]-[gene|4DE156D248FAF7DE3ED9AC35F006B5319A3C1BDA|fliT]-[gene|A6E7212D159F076F5D26F9C02F340B40C3667623|smiA]-[gene|06FEA5F205B40DD5CF8D9F1328E940D4543F4741|S1350]-[gene|37B8B671B84266A7D65B90A9077A0DFF458D1851|hpf]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|26577401], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]
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    genes
    [gene|4DBF4635B5C5A7541E8F97440D139DAA02547B99|yvyC]-[gene|C6012DEA301DF5B2DDD7E673A736BD3E5163F209|fliD]-[gene|4882FAD988FEDD0E72E4CAFB10C8DE61DDAC23B0|fliS]-[gene|4DE156D248FAF7DE3ED9AC35F006B5319A3C1BDA|fliT]
    description
    [Pubmed|8195064]

    sigma factors

  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|8195064], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]
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    Biological materials

    Mutant

  • BKE35330 ([gene|4882FAD988FEDD0E72E4CAFB10C8DE61DDAC23B0|fliS]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE35330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTGTCATCCTCCAAATT, downstream forward: _UP4_CGGCACGGATCAGGCGGGAT
  • BKK35330 ([gene|4882FAD988FEDD0E72E4CAFB10C8DE61DDAC23B0|fliS]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK35330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTGTCATCCTCCAAATT, downstream forward: _UP4_CGGCACGGATCAGGCGGGAT
  • References

    Reviews

  • 26490009
  • Original publications

  • 8195064,20534509,8195064,23144244,29061663,16021622,30068950