minor extracellular serine protease
function
protein degradation
product
minor extracellular serine protease
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.5|Utilization of proteins][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.2|Extracellular feeding proteases][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][SW|Categories] containing this gene/protein
[SW|utilization of nitrogen sources other than amino acids], [SW|proteolysis]This gene is a member of the following [SW|regulons]
[SW|CodY regulon], [SW|DnaA regulon], [SW|LexA regulon], [SW|PhoP regulon], [SW|SigH regulon]Gene
Coordinates on the chromosome (coding sequence)
3,907,844 -> 3,910,264
The protein
Protein family
peptidase S8 family (according to Swiss-Prot)[SW|Localization]
extracellular (signal peptide) [Pubmed|18957862]Expression and Regulation
Operon
''vpr'' [Pubmed|9353933][SW|Sigma factor]
[protein|search|SigH] [Pubmed|25666135]Regulation
expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|16291680]repressed when no DNA damage is present ([protein|search|LexA]) [Pubmed|16267290]repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|25666135]Regulatory mechanism
[protein|search|CodY]: transcription repression [Pubmed|25666135][protein|search|PhoP]: transcription activation [Pubmed|16291680][protein|search|LexA]: transcription repression [Pubmed|16267290][protein|search|DnaA]: transcription repression [Pubmed|26020636]References
Reviews
Original publications
2106512,24115457,16291680,16267290,18957862,25666135,26020636 
