mdtP [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

multidrug-efflux transporter

locus: BSU32880

pI: 9.84

mw: 57.00 kDa

function: multidrug resistance

product: multidrug-efflux transporter

essential: no

synonyms: yusP

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.3|Carbohydrate transporter]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|MdtR regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,374,956 -> 3,376,581

The protein

Protein family

• EmrB family (according to Swiss-Prot)

[SW|Localization]

• cell membrane (according to Swiss-Prot), membrane associated [Pubmed|18763711]

Expression and Regulation

Operon

• ''[protein|search|mdtR]-[protein|search|mdtP]'' [Pubmed|19286808]

Regulatory mechanism

• repression by [protein|search|MdtR] [Pubmed|19286808]

Biological materials

Mutant

• BP70 (spc) available in [SW|Fabian Commichau]'s lab

References

• 18763711,19286808