yxdM [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

ABC transporter (permease)

locus: BSU39630

pI: 9.27

mw: 70.00 kDa

function: export of toxic peptides

product: ABC transporter (permease)

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.3|Export of peptides]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|ABC transporters], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|YxdJ regulon]

Gene

Coordinates on the chromosome (coding sequence): 4,068,550 -> 4,070,418

The protein

Protein family

• ABC-4 integral membrane protein family (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|yxdL]-[protein|search|yxdM]-[protein|search|yxeA]'' [Pubmed|15289557]

Regulation

• induced by a cationic antimicrobial peptide, LL-37 ([protein|search|YxdJ]) [Pubmed| 21078927]

Regulatory mechanism

• [protein|search|YxdJ]: transcription activation [Pubmed|15289557]

References

• 10092453,15289557,21283517