SubtiBank SubtiBank
yxdM
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yxdM

[SW|ABC transporter] (permease)
locus
BSU_39630
pI
9.27
mw
70.35 kDa
protein length
622 aa Sequence Blast
gene length
1869 bp Sequence Blast
function
export of toxic peptides
product
[SW|ABC transporter] (permease)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.3|Export of peptides]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    4,068,550 4,070,418

    The protein

    Protein family

  • [SW|ABC-4 integral membrane protein family] (according to UniProt)
  • Paralogous protein(s)

  • [protein|AC7F08DC1DF7DD2F9AFF84041D357B286B1244AC|PsdB]
  • [SW|Localization]

  • cell membrane (according to UniProt)
  • Expression and Regulation

    Operons

    genes
    [gene|8B4267532B9788AEB5EF39E2695C1FDA494C7055|yxdL]-[gene|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM]-[gene|6D9153BA698101C3EE1CD68B76419ECD300740F8|yxeA]
    description
    [Pubmed|15289557]

    regulatory mechanism

  • [protein|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|YxdJ]: activation, [Pubmed|15289557], in [regulon|F3C5505E311E6DDABAFA87899F28CF6596CDBA63|YxdJ regulon]
  • regulation

  • induced by a cationic antimicrobial peptide, LL-37 ([protein|search|YxdJ]) [Pubmed| 21078927]
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    Biological materials

    Mutant

  • MGNA-B705 (yxdM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1704 NBRP B. subtilis, Japan]
  • BKE39630 ([gene|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCCCTTTTGTTTCTCGTGA, downstream forward: _UP4_ATGAACAAGTAAGGGGAGTG
  • BKK39630 ([gene|4423383A3F6DAFDFA210F4BEEF7D8CBEC674DCEA|yxdM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GGCCCTTTTGTTTCTCGTGA, downstream forward: _UP4_ATGAACAAGTAAGGGGAGTG
  • References

  • 10092453,15289557,21283517