SubtiBank SubtiBank
mhqD
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mhqD

may be involved in protection against methyl-hydroquinone
locus
BSU_19560
pI
5.62
mw
22.29 kDa
protein length
200 aa Sequence Blast
gene length
603 bp Sequence Blast
function
may be involved in protection against methyl-hydroquinone
product
unknown
essential
no
synonyms
yodD

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
  • Gene

    Coordinates
    2,128,464 2,129,066

    The protein

    Protein family

  • [SW|AB hydrolase superfamily] (according to UniProt)
  • Structure

  • [PDB|2H1I] (from B. cereus, 59% identity)
  • Expression and Regulation

    Operons

    genes
    [gene|A1CB3DCF2EC78B9B0585CA6AC6F5BB37B8AF0208|mhqE]-[gene|43CD556065D2EF14365C78E014B7B2051CA0C78F|mhqD]
    description
    [Pubmed|17725564]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|17725564], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulatory mechanism

  • [protein|997B828A99D6D8460712C18ED0CE566B285C22DC|MhqR]: repression, [Pubmed|17725564], in [regulon|997B828A99D6D8460712C18ED0CE566B285C22DC|MhqR regulon]
  • regulation

  • induced by 2-methylhydroquinone ([protein|search|MhqR]) [Pubmed|17725564]
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    Biological materials

    Mutant

  • MGNA-B435 (yodD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1434 NBRP B. subtilis, Japan]
  • BKE19560 ([gene|43CD556065D2EF14365C78E014B7B2051CA0C78F|mhqD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE19560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATGCTTCATTATAAATTCCC, downstream forward: _UP4_TAAAAAAACCTTAGTCCGGA
  • BKK19560 ([gene|43CD556065D2EF14365C78E014B7B2051CA0C78F|mhqD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK19560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATGCTTCATTATAAATTCCC, downstream forward: _UP4_TAAAAAAACCTTAGTCCGGA
  • References

  • 17407181,17725564