The second international online conference #Subtillery2021 will be held 14th - 18th June - save the date, for more information see the conference website!

The 21st International Conference on Bacilli has been postponed to 2022 and will take place in Prague.

yxlH

similar to multidrug-efflux transporter

locus: BSU_38640

pI: 9.02

mw: 43.80 kDa

protein length: 400 aa

gene length: 1203 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 3,966,745 3,967,947

The protein

Protein family

• [SW|major facilitator superfamily] (according to UniProt)
• [SW|TCR/Tet family] (according to UniProt)

Structure

• [PDB|3WDO] (26% identity) [pubmed|23950222]

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|43917869D4E75015CEA23109E8F97DFFECD39C14|yxlH]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-B754 (yxlH::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1753 NBRP B. subtilis, Japan]
• BKE38640 ([gene|43917869D4E75015CEA23109E8F97DFFECD39C14|yxlH]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTATCTCTCCACCCCT, downstream forward: _UP4_GCGCAAAAACGTAACATGAT
• BKK38640 ([gene|43917869D4E75015CEA23109E8F97DFFECD39C14|yxlH]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGTATCTCTCCACCCCT, downstream forward: _UP4_GCGCAAAAACGTAACATGAT

References

Research papers

• 23950222