SubtiBank SubtiBank
yitJ [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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yitJ [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

methionine synthase
locus
BSU11010
pI
5.34
mw
67.00 kDa
function
methionine biosynthesis
product
methionine synthase
essential
no
ec
2.1.1.13
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.11|Biosynthesis/ acquisition of methionine/ S-adenosylmethionine/ based on similarity]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • [SW|Categories] containing this gene/protein

  • [SW|membrane proteins], [SW|biosynthesis/ acquisition of amino acids]

    • This gene is a member of the following [SW|regulons]

  • [SW|S-box]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,178,757 -> 1,180,595

    The protein

    [SW|Localization]

  • membrane associated [Pubmed|18763711]

    • Expression and Regulation

    Operon

  • ''[protein|search|yitJ]-[protein|search|yitI]-[protein|search|yitH]'' [Pubmed|10094622]

    • Regulation

  • induced by methionine starvation ([protein|search|S-box]) [Pubmed|10094622]
  • repressed by casamino acids [Pubmed|12107147]

    • Regulatory mechanism

  • [protein|search|S-box]: transcription termination/ antitermination, the [protein|search|S-box] [SW|riboswitch] binds S-adenosylmethionine resulting in termination [Pubmed|10094622]

    • References

    The [protein|search|S-box]

  • 19258532,10094622,18039762,20951706,22543867

    • Other publications

  • 19779461,12107147,18763711,22960854