frlR

transcriptional regulator ([SW|GntR family])

locus: BSU_32560

pI: 6.42

mw: 27.36 kDa

protein length: 242 aa

gene length: 729 bp

function: regulation of utilization of sugar amines

product: transcriptional regulator ([SW|GntR family])

essential: no

synonyms: yurK

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.17|Utilization of amino sugars]
• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.3|Utilization of amino sugars]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

Gene

Coordinates: 3,346,298 3,347,026

The protein

Protein family

• [SW|GntR family] of transcription factors

[SW|Domains]

• [SW|HTH gntR-type domain] (aa 8-76) (according to UniProt)

Structure

• [PDB|2IKK] (C-terminal domain)

Biological materials

Mutant

• MGNA-A557 (yurK::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/557 NBRP B. subtilis, Japan]
• BKE32560 ([gene|412A1DBBE7F87765DEBEEAAE02A047636A354D5E|frlR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE32560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGGGTAGCCTCCTTTTA, downstream forward: _UP4_TAACAGGCATAAAAAACGAG
• BKK32560 ([gene|412A1DBBE7F87765DEBEEAAE02A047636A354D5E|frlR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK32560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAGGGTAGCCTCCTTTTA, downstream forward: _UP4_TAACAGGCATAAAAAACGAG

References

• 21347729,21398478