The second international online conference
#Subtillery2021 will be held 14th - 18th June - save the date, for more information see the
conference website!
The 21st
International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
yfmI
similar to macrolide-efflux transporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.12|Other transporters][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
819,311 820,531
The protein
Protein family
[SW|major facilitator superfamily] (according to UniProt)[SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|3DFC1A118B346C7939851BF711FFA31E04A698E8|yfmI]-[gene|B61458337D96A0CF8D0778A03A0DB68B566913D8|yfmJ]
description
[Pubmed|22383849]
regulatory mechanism
[protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: activation, [Pubmed|14651647], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon][protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]regulation
expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]additional information
A [protein|search|ncRNA] is predicted between '[protein|3DFC1A118B346C7939851BF711FFA31E04A698E8|YfmI]' and '[protein|893BB8D1B43F10B46BB7F2DBFE9BE63E9AEEE8EB|YfmG]' [PubMed|20525796]view in new tabBiological materials
Mutant
MGNA-C242 (yfmI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2240 NBRP B. subtilis, Japan]BKE07460 ([gene|3DFC1A118B346C7939851BF711FFA31E04A698E8|yfmI]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGTATCCTCCCTTGGA, downstream forward: _UP4_TAATAAATATATAAAATTTABKK07460 ([gene|3DFC1A118B346C7939851BF711FFA31E04A698E8|yfmI]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGTATCCTCCCTTGGA, downstream forward: _UP4_TAATAAATATATAAAATTTAGP2580 ([gene|3DFC1A118B346C7939851BF711FFA31E04A698E8|yfmI]::tet comIQ12L) (in DK1042) available in [SW|Jörg Stülke]'s labReferences
14651647,20525796,20817675