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spoVFA
dipicolinate synthase (subunit A)
function
dipicolic acid production
product
dipicolinate synthase (subunit A)
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.3|Biosynthesis of dipicolinate][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]Gene
Coordinates
1,744,367 1,745,260
The protein
Catalyzed reaction/ biological activity
(S)-2,3-dihydrodipicolinate + NADP+ --> dipicolinate + H+ + NADPH (according to UniProt)Structure
[PDB|2RIR]Expression and Regulation
Operons
genes
[gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]-[gene|4D93A13DB9DC55A49525BFF4FD589F4FF67D50E8|spoVFB]-[gene|564A2F43F8AABE97FC8F0B1B3382A9F31F02FA18|asd]-[gene|6D6718AC72C9D86EDE16B191EDAB3ABA488B689B|dapG]-[gene|00B4CA4E25858A56F9D4E0ADEE2643F203FEC613|dapA]
description
[Pubmed|8098035]
sigma factors
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|15699190,8098035], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]regulation
expressed late during sporulation in the mother cell ([protein|search|SigK]) [Pubmed|15699190,8098035]view in new tabBiological materials
Mutant
BKE16730 ([gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTAAACGTTCACCTTC, downstream forward: _UP4_CAAGCTGAGGAGGGGAAATABKK16730 ([gene|3DA80060554B78E9DC2189CECB78680095B08B32|spoVFA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16730 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCTAAACGTTCACCTTC, downstream forward: _UP4_CAAGCTGAGGAGGGGAAATAReferences
