yukD [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

Ubiquitin-like protein, part of the type VII protein secretion system YukD-YukC-YukB-YueB-YueC, putative bacteriocin

locus: BSU31900

pI: 6.31

mw: 8.00 kDa

function: export of YukE

product: ubiquitin-like protein, part of the type VII protein secretion system, putative bacteriocin

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.16|Biosynthesis of antibacterial compounds/ based on similarity]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of antibacterial compounds], [SW|protein secretion]

This gene is a member of the following [SW|regulons]

• [SW|DegU regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,275,832 -> 3,276,071

Phenotypes of a mutant

• loss of secretion of [protein|search|YukE] [Pubmed|24798022]

The protein

Structure

• [PDB|2BPS]

Expression and Regulation

Operon

• ''[protein|search|yukE]-[protein|search|yukD]-[protein|search|yukC]-[protein|search|yukB]-[protein|search|yueB]-[protein|search|yueC]'' [Pubmed|22383849,15576783]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|22383849]

Regulation

• not expressed in the lab strain 168, due to lack of [protein|search|DegU]-P [Pubmed|23861817]
• expressed in the stationary phase [Pubmed|23861817]

Regulatory mechanism

• [protein|search|DegU]-P: transcription activation [Pubmed|23861817]

References

Reviews

• 19155186,11973144

Original publications

• 15576783,16845009,22383849,23861817,15978580,24798022