sigE [Mon Aug 31 2015 13:54:11 GMT+0200 (CEST)]

RNA polymerase sporulation mother cell-specific (early) sigma factor SigE

Locus: BSU15320

Isoelectric point: 9.21

Molecular weight: 27.00 kDa

Function: transcription of sporulation genes (early mother cell)

Product: RNA polymerase sporulation mother cell-specific
(early) sigma factor SigE

Essential: no

Synonyms: spoIIGB

Genomic Context

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Categories containing this gene/protein

• Information processing → RNA synthesis and degradation → Transcription → Sigma factors
• Information processing → Regulation of gene expression → Sigma factors and their control → Sigma factors
• Groups of genes → Efp-dependent proteins

Syns: spoIIGB

Categories containing this gene/protein

• transcription, sigma factors and their control, sporulation proteins

This gene is a member of the following regulons

• SinR regulon, Spo0A regulon, Efp-dependent proteins

The protein

Catalyzed reaction/ biological activity

• RNA polymerase sigma factor, active in the mother cell

Protein family

• sigma-70 factor family (according to Swiss-Prot)

Interactions

• SigE-(RpoB-RpoC)
• SpoIIGA-SigE (Processing) PubMed
• CsfB-SigE to inhibit SigE activity PubMed

Expression and Regulation

Operon

• spoIIGA-sigE-sigG PubMed

Sigma factor

• SigA PubMed

Regulation

• expressed under conditions that trigger sporulation (Spo0A) PubMed

Regulatory mechanism

• repression by SinR
• Spo0A: transcription activation PubMed

Labs working on this gene/protein

• Bill Haldenwang, San Antonio, USA
• Charles Moran, Emory University, NC, USA homepage

References

Reviews

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The SigE regulon

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Original Publications

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