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murC [Tue Dec 29 2015 17:33:11 GMT+0100 (CET)]
UDP-N-acetylmuramoyl-L-alanine synthetase
function
peptidoglycan precursor biosynthesis
product
UDP-N-acetylmuramoyl-L-alanine synthetase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|essential genes]Gene
Coordinates on the chromosome (coding sequence)
3,048,177 -> 3,049,475
Phenotypes of a mutant
essential [Pubmed|12682299]murC is dispensable in wall-less L-forms [Pubmed|24704074]The protein
Catalyzed reaction/ biological activity
ATP UDP-N-acetylmuramate L-alanine = ADP phosphate UDP-N-acetylmuramoyl-L-alanine (according to Swiss-Prot)Protein family
murCDEF family (according to Swiss-Prot)[SW|Localization]
cytoplasm (Homogeneous) [Pubmed|16479537]Expression and Regulation
Operon
''[protein|search|murC]'' [Pubmed|8733232]References
18063720,8733232,24704074,16479537