SubtiBank SubtiBank
murC [Tue Dec 29 2015 17:33:11 GMT+0100 (CET)]
Save the date! 20th International Conference on Bacilli and Gram-Positive Bacteria. Washington, D.C. July 23-26, 2019.

murC [Tue Dec 29 2015 17:33:11 GMT+0100 (CET)]

UDP-N-acetylmuramoyl-L-alanine synthetase
locus
BSU29790
pI
5.00
mw
48.00 kDa
function
peptidoglycan precursor biosynthesis
product
UDP-N-acetylmuramoyl-L-alanine synthetase
essential
yes
ec
6.3.2.8
synonyms
ytxF

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|essential genes]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,048,177 -> 3,049,475

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • murC is dispensable in wall-less L-forms [Pubmed|24704074]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP UDP-N-acetylmuramate L-alanine = ADP phosphate UDP-N-acetylmuramoyl-L-alanine (according to Swiss-Prot)
  • Protein family

  • murCDEF family (according to Swiss-Prot)
  • [SW|Localization]

  • cytoplasm (Homogeneous) [Pubmed|16479537]
  • Expression and Regulation

    Operon

  • ''[protein|search|murC]'' [Pubmed|8733232]
  • References

  • 18063720,8733232,24704074,16479537