mother-cell specific penicillin-binding protein (spore cortex)
function
spore morphogenesis
product
penicillin-binding protein (spore cortex)
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.7|Penicillin-binding proteins][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|sporulation proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigE regulon], [SW|SpoIIID regulon]The protein
Catalyzed reaction/ biological activity
protects [SW|SpoVE] from proteolytic degradation [Pubmed|20417640]Paralogous protein(s)
[protein|search|PbpB][SW|Domains]
C-terminal [SW|PASTA domain] (aa 580-638) [Pubmed|25481876]Effectors of protein activity
intramolecular disulfide bonds between two Cys residues are reduced by [protein|search|StoA], this is rquired for activity of SpoVD [Pubmed|19919673][SW|Localization]
intermembrane space that separates forespores from mother cells [Pubmed|19919673][SW|Interactions]
[SW|SpoVD]-[protein|search|StoA] [Pubmed|19919673][SW|SpoVD]-[SW|SpoVE] [Pubmed|20417640]Expression and Regulation
Operon
''[SW|spoVD]'' [Pubmed|8436954][SW|Sigma factor]
[protein|search|SigE] [Pubmed|15699190,15758244]Regulation
expressed during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|15699190,15758244]Regulatory mechanism
[SW|SpoIIID]: transcription repression [Pubmed|9006059]Biological materials
Mutant
1A975 ( ''spoVD''::''cat''), [Pubmed|19212404], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A975&Search=1A975 BGSC]References
Reviews
Original Publications
9006059,8289242,15699190,15758244,8436954,9006059,19919673,20417640,23789716,25481876 
