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apt [Mon Aug 31 2015 13:55:59 GMT+0200 (CEST)]
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apt [Mon Aug 31 2015 13:55:59 GMT+0200 (CEST)]

adenine phosphoribosyltransferase, universally conserved protein
locus
BSU27610
pI
4.70
mw
18.00 kDa
function
purine salvage and interconversion
product
adenine phosphoribosyltransferase
essential
no
ec
2.4.2.7
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.3|Purine salvage and interconversion]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
  • [category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of nucleotides], [SW|universally conserved proteins], [SW|phosphoproteins]
  • The protein

    Catalyzed reaction/ biological activity

  • AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
  • Protein family

  • purine/pyrimidine phosphoribosyltransferase family (according to Swiss-Prot)
  • Modification

  • phosphorylated on Arg-85 [Pubmed|22517742]
  • Structure

  • [PDB|2DY0] (from ''Escherichia coli k12'', 56% identity, 66% similarity)
  • Additional information

  • [SW|universally conserved protein]
  • Expression and Regulation

    Operon

  • ''[protein|search|recJ]-[protein|search|apt]'' [Pubmed|15241682]
  • References

  • 3110131,15241682,22517742