rtpA [2017-8-11 16:0:3]

anti-TRAP

locus: BSU02530

pI: 4.86

mw: 5.51 kDa

protein length: 53 aa

gene length: 159 bp

function: regulation of tryptophan biosynthesis

product: anti-TRAP

essential: no

synonyms: yczA

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.13|Biosynthesis/ acquisition of aromatic amino acids]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.7|Control of transcription factor (other than two-component system)]

Gene

Coordinates: 277,160 → 277,321

The protein

Structure

• [PDB|1N53] (structure of T box RNA), [PDB|2BX9], [PDB|2ZP9] (complex with [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|MtrB])

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|354C71C2F6AFE620866D90595E6AC6CEFA5705C3|rtpA]-[gene|EAE919A6088F1A455B6FCE62BA8CCBD05C1F98D5|ycbK]
  description: [Pubmed|10706627]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|10706627], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  regulatory mechanism

  • [regulon|T-box|T-box]: transcription termination/ antitermination, [protein|E030E80134E9DED6ADBC73C7C7435024CDFD38B9|MtrB] [pubmed|10706627], in [regulon|T-box|T-box]

  regulation

  • ''[protein|search|rtpA]'': induced by tryptophan limitation ([protein|search|T-box] in the mRNA leader) [Pubmed|10706627]

References

Reviews

• 16285852,19258532

Original Publications

• 15213402,16306262,15099736,15743934,11786553,11566976,15023340,18178730,12386162,11557884,10706627,18334255,12855807,20713740,24682818