SubtiBank SubtiBank
menA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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menA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
locus
BSU38490
pI
9.00
mw
33.00 kDa
function
biosynthesis of menaquinone
product
probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
essential
yes
ec
2.5.1.74
synonyms
ywaB, ipa-6d

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.8|Biosynthesis of menaquinone]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors], [SW|essential genes], [SW|membrane proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,950,726 -> 3,951,661

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Protein family

  • menA family (according to Swiss-Prot)
  • Structure

  • [PDB|3BYV] (from ''Toxoplasma gondii'', 30% identity in a 25% fragment) [Pubmed|19197235]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''menA'' [Pubmed|9353933]
  • References

  • 9353933,19197235