menA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase

locus: BSU38490

pI: 9.00

mw: 33.00 kDa

function: biosynthesis of menaquinone

product: probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase

essential: yes

ec: 2.5.1.74

synonyms: ywaB, ipa-6d

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.8|Biosynthesis of menaquinone]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|biosynthesis of cofactors], [SW|essential genes], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 3,950,726 -> 3,951,661

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Protein family

• menA family (according to Swiss-Prot)

Structure

• [PDB|3BYV] (from ''Toxoplasma gondii'', 30% identity in a 25% fragment) [Pubmed|19197235]

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''menA'' [Pubmed|9353933]

References

• 9353933,19197235