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yitM
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yitM

[SW|biofilm] toxin
locus
BSU_11040
pI
4.77
mw
21.32 kDa
protein length
194 aa Sequence Blast
gene length
585 bp Sequence Blast
function
protection of B. subtilis biofilms against competitors
product
biofilm toxin
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.3|Toxins, antitoxins and immunity/ Additional genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    1,182,448 1,183,032

    The protein

    Paralogous protein(s)

  • [protein|820635420B3980B620F3E3D7ACF7EDE9DC6275AD|SdpC]

    • [SW|Localization]

  • membrane (according to UniProt)

    • Expression and Regulation

    Operons

    genes
    [gene|330CB6A25181F7AFD3C63F73CA21A3428882D100|yitM]
    description
    [pubmed|22383849]
    view in new tab

    genes
    [gene|FBA412B070CE4FFE554F2657E0F745EF5C853B8A|yitP]-[gene|81E929FD7F66A996300C8412BE172883C262BD67|yitO]-[gene|330CB6A25181F7AFD3C63F73CA21A3428882D100|yitM]
    description
    [Pubmed|17850253]

    regulatory mechanism

  • [protein|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU]: activation, [pubmed|17850253], in [regulon|D343D2096664A972026D911E7A17A35C7B1CD1C9|DegU regulon]

    • regulation

  • induced in biofilms ([SW|DegU]) [Pubmed|17850253]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B213 (yitM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1212 NBRP B. subtilis, Japan]
  • BKE11040 ([gene|330CB6A25181F7AFD3C63F73CA21A3428882D100|yitM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11040 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAAATACTAGAAACGCCT, downstream forward: _UP4_TAGACATAAAAAAACGGCTC
  • BKK11040 ([gene|330CB6A25181F7AFD3C63F73CA21A3428882D100|yitM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11040 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAAAATACTAGAAACGCCT, downstream forward: _UP4_TAGACATAAAAAAACGGCTC

    • References

    Research papers

  • 31622331,17850253