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lgt [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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lgt [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

prolipoprotein diacylglyceryl transferase
locus
BSU34990
pI
8.00
mw
30.00 kDa
function
lipomodification of lipoproteins
product
prolipoprotein diacylglyceryl transferase
essential
no
ec
2.4.99.-
synonyms
gerF, yvoC

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.1|Protein maturation]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.4|Germination] → [category|SW 4.2.4.2|Additional germination proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|protein modification], [SW|germination], [SW|membrane proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,593,419 -> 3,594,228

    Phenotypes of a mutant

  • reduced ability of spores to germinate with alanine due ti reduced activity of the [SW|GerAA]-[SW|GerAB]-[SW|GerAC] germinant receptor [Pubmed|15126458]
  • inactivation of ''[SW|lgt]'' reduces sporulation efficiency to 7.7% that of wild type cells [Pubmed|26735940]
  • The protein

    Protein family

  • lgt family (according to Swiss-Prot)
  • [SW|Localization]

  • membrane associated [Pubmed|18763711]
  • [SW|Interactions]

  • [SW|GerAC]-[protein|search|Lgt] to fix [SW|GerAC] to diacylglycerol in the membrane [Pubmed|15126458]
  • [protein|search|GerD]-[protein|search|Lgt] to fix [protein|search|GerD] to diacylglycerol in the membrane [Pubmed|22493018]
  • Expression and Regulation

    Operon

  • ''[protein|search|hprK]-[protein|search|lgt]-[protein|search|yvoD]-[protein|search|yvoE]-[protein|search|yvoF]'' [Pubmed|9465101]
  • Biological materials

    Mutant

  • GP851 (deletion of ''[protein|search|lgt]-[protein|search|yvoD]-[protein|search|yvoE]-[protein|search|yvoF]'', replaced by aphA3), available in the [SW|Stülke] lab
  • 1G22 ( ''lgt''::''erm''), [Pubmed|15126458], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1G22&Search=1G22 BGSC]
  • References

    Reviews

  • 21663440
  • Original publications

  • 9882689,10096076,15126458,18763711,9465101,22493018,9846746,26735940
  • Lgt in other organisms

  • 22287519