SubtiBank SubtiBank
yxkC
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yxkC

unknown
locus
BSU_38850
pI
9.29
mw
22.00 kDa
protein length
213 aa Sequence Blast
gene length
642 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

    • Gene

    Coordinates
    3,989,232 3,989,873

    The protein

    [SW|Domains]

  • [SW|DUF4352] (aa 46 ... 175)(according to UniProt)

    • Structure

  • [PDB|4LES] (from B. anthracis, corresponds to aa 79 ... 213, 30% identity)

    • [SW|Localization]

  • extracellular (signal peptide) [Pubmed|18957862]
  • membrane [Pubmed|18763711]

    • Expression and Regulation

    Operons

    genes
    [gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]
    description
    [Pubmed|10746760]

    sigma factors

  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|15033535], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]

    • regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: activation, [Pubmed|12823818], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon]

    • regulation

  • repressed in the absence of good nitrogen sources (glutamine or ammonium) ([protein|search|TnrA]) [Pubmed|12823818]
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    Biological materials

    Mutant

  • MGNA-B737 (yxkC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1736 NBRP B. subtilis, Japan]
  • BKE38850 (''[gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]''::''erm'', available in the BGSC and in [SW|Jörg Stülke]'s lab) [pubmed|28189581]
  • GP1824 (''[gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]''::''erm'', available in [SW|Jörg Stülke]'s lab)
  • BKE38850 ([gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAAAAAGTTACGTTGAT, downstream forward: _UP4_TAACAGCTAACAAGGGTGCC
  • BKK38850 ([gene|2BFDEB28F3B2937DCECB2C45B40D4657B4613ED9|yxkC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38850 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAAAAAGTTACGTTGAT, downstream forward: _UP4_TAACAGCTAACAAGGGTGCC

    • References

  • 15033535,12823818,18957862,18763711,10746760,23033921