small acid-soluble spore protein (major beta-type SASP)
function
protection of spore DNA
product
small acid-soluble spore protein (major beta-type SASP)
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.3|Small acid-soluble spore proteins][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue][SW|Categories] containing this gene/protein
[SW|sporulation proteins], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|SigG regulon], [SW|SpoVT regulon]Gene
Phenotypes of a mutant
a ''[protein|search|sspB]'' mutant is sensitive to ionizing radiation [Pubmed|24123749]The protein
Protein family
alpha/beta-type SASP family (according to Swiss-Prot)Modification
phosphorylated on Ser-6, Ser-7, and Ser-45 [Pubmed|26381121]Structure
[PDB|2Z3X]Expression and Regulation
Operon
''sspB'' [Pubmed|3009398][SW|Sigma factor]
[protein|search|SigG] [Pubmed|15699190]Regulation
expressed during sporulation in the forespore ([protein|search|SigG], [SW|SpoVT]) [Pubmed|15699190,8755877]the mRNA accumulates in a ''[protein|search|ymdB]'' mutant [Pubmed|24163345]Regulatory mechanism
[SW|SpoVT]: transcription activation [Pubmed|8755877]Biological materials
Mutant
1S111 (no resistance), [Pubmed|3087950], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S111&Search=1S111 BGSC]1S113 (no resistance), [Pubmed|3125155], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S113&Search=1S113 BGSC]GFP fusion
GP996 (cat, based on pSG1151), available in the [SW|Stülke] labReferences
16707666,1900507,2456528,3009398,11092849,7608092,15458366,19542328,8755877,23064347,3087950,3125155,24163345,24123749,26381121 
