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ydaP [2017-05-09 15:36:34]
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ydaP [2017-05-09 15:36:34]

general stress protein, required for survival of ethanol stress, putative pyruvate oxidase
locus
BSU04340
pI
5.22
mw
62.97 kDa
protein length
574 aa Sequence Blast
gene length
1722 bp Sequence Blast
function
unknown
product
putative pyruvate oxidase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    488,830 → 490,554

    The protein

    Paralogous protein(s)

  • [protein|AAA45830B9C5428CADFA5551D33B513E9B1B7C8E|AlsS], [protein|E6EDDB6D1EDA85D73A0B78A656511D38346A625B|IlvB]

    • Structure

  • [PDB|4KGD] (the enzyme from Lactobacillus plantarum, 37% identity, 70% similarity) [Pubmed|23748673]

    • Expression and Regulation

    Operons

    genes
    [gene|2883FC60CD69948D5C43BDDFEFBE7A1CA7C743C7|ydaP]
    description
    [Pubmed|10220166]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]
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    Biological materials

    Mutant

  • MGNA-C115 (ydaP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2113 NBRP B. subtilis, Japan]
  • GP457 (spc), available in [SW|Jörg Stülke]'s lab

    • References

  • 10220166,23748673,15805528,22730460