tcyA [Mon Aug 31 2015 13:52:26 GMT+0200 (CEST)]

cystine ABC transporter (binding protein)

locus: BSU03610

pI: 9.12

mw: 29.00 kDa

function: cystine uptake

product: cystine ABC transporter (binding protein)

essential: no

synonyms: yckK

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.2|Uptake of amino acids]
• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.9|Biosynthesis/ acquisition of cysteine]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

syns: yckK

[SW|Categories] containing this gene/protein

• [SW|ABC transporters], [SW|biosynthesis/ acquisition of amino acids], [SW|membrane proteins]

The protein

Protein family

• bacterial solute-binding protein 3 family (according to Swiss-Prot)

[SW|Localization]

• attached to the membrane via [protein|search|TcyB] [Pubmed|10092453]

[SW|Interactions]

• [protein|search|TcyC]-[protein|search|TcyB]-[protein|search|TcyA] [Pubmed|10092453]

Expression and Regulation

Operon

• ''[protein|search|tcyA]-[protein|search|tcyB]-[protein|search|tcyC]'' (putative) [Pubmed|15262924]

Regulation

• very weakly expressed under all conditions [Pubmed|15262924]
• strongly repressed in response to glucose starvation in M9 medium [Pubmed|23033921]

References

• 15262924,10092453,7551042,23033921