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qcrB [2018-07-03 10:45:24]
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qcrB [2018-07-03 10:45:24]

menaquinol:cytochrome c oxidoreductase (cytochrome b subunit), component of the cytochrome bc complex
locus
BSU22550
pI
7.44
mw
25.34 kDa
protein length
224 aa Sequence Blast
gene length
672 bp Sequence Blast
function
respiration
product
menaquinol:cytochrome c oxidoreductase (cytochrome b subunit)
essential
no
synonyms
bfcB,petB

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.2|Respiration] → [category|SW 2.1.2.4|Respiration/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    2,363,913 → 2,364,587

    The protein

    Protein family

  • peptidase M20A family (according to Swiss-Prot)
  • [SW|Cofactors]

  • heme, covalently bound to Cys-43 [pubmed|9535866]
  • Structure

  • [PDB|1VFS] (43% identity)
  • [SW|Localization]

  • cell membrane [Pubmed|23880299]
  • Expression and Regulation

    Operons

    genes
    [gene|D4AF96C936093BA44E46FF92A3EDE437495B0923|qcrA]-[gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]-[gene|F2973C512AFB4B9F8FE0CCAF09646E60F886C013|qcrC]
    description
    [Pubmed|7592464]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|7592464], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulatory mechanism

  • [protein|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD]: activation, [Pubmed|8631715], in [regulon|1E829D639BADDC6BDC9B5FB4C97A632A53FDDB24|ResD regulon]
  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, [Pubmed|12850135], in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]
  • [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB]: repression, [Pubmed|20817675], in [regulon|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB regulon]
  • regulation

  • induced by oxygen limitation ([protein|search|ResD]) [Pubmed|8631715]
  • view in new tab

    Biological materials

    Mutant

  • BKE22550 (Δ[gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCAGTCATAAATTTTGTTCA, downstream forward: _UP4_TAAACTCTTGATCTGCGAAT
  • BKK22550 (Δ[gene|1DC5C6DAF0AB1EB59BC9361DC1161E75F99AFE33|qcrB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CCAGTCATAAATTTTGTTCA, downstream forward: _UP4_TAAACTCTTGATCTGCGAAT
  • References

  • 8631715,7592464,12107147,12850135,20817675,23880299,9535866,27503613