SubtiBank SubtiBank
yvrB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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yvrB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

ABC transporter (ATP binding domain), similar to iron permease
locus
BSU33170
pI
11.00
mw
37.00 kDa
function
unknown
product
ABC transporter (ATP binding domain)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.7|Uptake of cofactors]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.13|Biosynthesis/ acquisition of cobalamine (B12))]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|B12 riboswitch]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,402,469 -> 3,403,530

    The protein

    Structure

  • [PDB|4R9U], the ''E. coli'' BtuC-BtuD complex, BtuC shares 40% identity, 71% similarity with YvrB, [Pubmed|25402482]
  • Expression and Regulation

    Operon

  • ''[SW|yvrC]-[SW|yvrB]-[SW|yvrA]-[SW|yvqK]'' [Pubmed|]
  • Regulation

  • expression is decreased in the presence of cobalamin (vitamin B12) ([SW|B12 riboswitch]) [Pubmed|14704351]
  • Regulatory mechanism

  • [SW|B12 riboswitch]: transcription termination upon binding of B12 [Pubmed|14704351]
  • References

  • 10092453,25402482,14704351