SubtiBank SubtiBank
cmk
An ordered knock out library of all non-essential genes in B. subtilis is now available at Addgene. Information on ordering a copy can be found here. See Koo et al. 2017 for details about library construction.

cmk

cytidylate kinase (CMP, dCMP)
locus
BSU22890
pI
5.00
mw
24.95 kDa
protein length
224 aa Sequence Blast
gene length
672 bp Sequence Blast
function
synthesis of CTP and dCTP
product
cytidylate kinase (CMP, dCMP)
essential
yes
ec
2.7.4.14
synonyms
jofC, ypfC

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.5|Nucleotide metabolism] → [category|SW 2.5.2|Biosynthesis/ acquisition of nucleotides] → [category|SW 2.5.2.4|Biosynthesis/ acquisition of pyrimidine nucleotides]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • Gene

    Coordinates
    2,396,045 → 2,396,719

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Catalyzed reaction/ biological activity

  • ATP + (d)CMP = ADP + (d)CDP (according to Swiss-Prot)
  • Protein family

  • Type 1 subfamily (according to Swiss-Prot)
  • Structure

  • [PDB|1CKE] (from ''Escherichia coli'', 38% identity, 54% similarity) [Pubmed|9862805]
  • References

  • 9126287