spoIIM [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

required for dissolution of the septal cell wall

locus: BSU23530

pI: 9.00

mw: 24.00 kDa

function: dissolution of the septal cell wall

product: sporulation protein

essential: no

synonyms

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

[SW|Categories] containing this gene/protein

• [SW|cell wall/ other], [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigE regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,450,403 -> 2,451,047

The protein

[SW|Localization]

• cytoplasm (according to Swiss-Prot)
• the complex of [SW|SpoIID], [SW|SpoIIM], and [SW|SpoIIP] localizes at the leading edge of the mother cell engulfing membrane and is essential and rate limiting for membrane migration [Pubmed|20382772,12502745]

[SW|Interactions]

• [SW|SpoIIP]-[SW|SpoIIM] [Pubmed|17376078]

Expression and Regulation

Operon

• ''spoIIM'' [Pubmed|8501065]

[SW|Sigma factor]

• [protein|search|SigE] [Pubmed|8501065]

Regulation

• expressed early during sporulation in the mother cell ([protein|search|SigE]) [Pubmed|8501065]
• subject to negative control by [protein|search|YlbO] [Pubmed|15383836]

References

• 17376078,11886548,15752199,8501065,15383836,23859254,20382772,12502745