SubtiBank SubtiBank
secE
An ordered knock out library of all non-essential genes in B. subtilis is now available at Addgene. Information on ordering a copy can be found here. See Koo et al. 2017 for details about library construction.

secE

preprotein translocase subunit
locus
BSU01000
pI
10.47
mw
6.79 kDa
protein length
gene length
177 bp Sequence Blast
function
protein secretion
product
preprotein translocase subunit
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    117,532 → 117,711

    Phenotypes of a mutant

  • essential [Pubmed|12682299] [Pubmed|7968510]
  • The protein

    Protein family

  • secE/SEC61-gamma family (according to Swiss-Prot)
  • [SW|Domains]

  • transmembrane protein with a single TM domain
  • Structure

  • [PDB|3DL8] (structure of the ([protein|5350DC618130E013757EE667B9AFC5F2EC68EC08|SecY]-[protein|1007EA15FB7AF81A44400287DB68BCC497158ACF|SecE]-[protein|D8851F453E5EF18D36F25834A8CB9C61EAF15E44|SecG])-[protein|AD7CD451B4AE638A719C91780339784A7FF0F248|SecA] complex) [Pubmed|18923516]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Additional information

  • B. subtilis secE complements the secretion phenotype of a cold sensitive E. coli secE mutant.
  • References

    Reviews

  • 25212246,27890920
  • Original publications

  • 7968510,18923516,26747607