azoR2 [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

similar to NAD(P)H dehydrogenase (quinone)

locus: BSU33540

pI: 5.11

mw: 23.00 kDa

function: resistance to 2-methylhydroquinone

product: azoreductase

essential: no

synonyms: yvaB

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins], [SW|resistance against oxidative and electrophile stress]

This gene is a member of the following [SW|regulons]

• [SW|MhqR regulon], [SW|SigG regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,445,442 -> 3,446,077

The protein

Protein family

• azoreductase type 1 family (according to Swiss-Prot)

Paralogous protein(s)

• [SW|AzoR1]

Structure

• [PDB|3P0R] (from B. anthracis, 43% identity, 61% similarity)

Expression and Regulation

Operon

• ''azoR2'' [Pubmed|17725564]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|17725564], [protein|search|SigG] [Pubmed|16497325]

Regulation

• induced by catechol and 2-methylhydroquinone (2-MHQ) ([protein|search|MhqR]) [Pubmed|17725564]
• repressed by casamino acids [Pubmed|12107147]

Regulatory mechanism

• [protein|search|MhqR]: transcription repression [Pubmed|17725564]

References

• 17725564,18208493,16497325,12107147