SubtiBank SubtiBank
murJ [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]
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murJ [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

lipid II flippase
locus
BSU30050
pI
10.00
mw
59.00 kDa
function
export of lipid II
product
lipid II flippase
essential
no
synonyms
ytgP

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|membrane proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,073,531 -> 3,075,165

    Phenotypes of a mutant

  • an ''[protein|search|amj] [protein|search|murJ]'' double mutant is not viable [Pubmed|25918422]
  • a ''[protein|search|sigM] [protein|search|murJ]'' double mutant is not viable (due to the lack of both lipid II flippases) [Pubmed|25918422]
  • mutants lacking [protein|search|MurJ] produce long cells and chains of cells [Pubmed|19648239]
  • The protein

    Protein family

  • [SW|MOP exporter family]
  • Paralogous protein(s)

  • [SW|SpoVB], [protein|search|YabM], [protein|search|YkvU]
  • Biological materials

    Mutant

  • MGNA-A012 (ytgP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/12 NBRP B. subtilis, Japan]
  • References

    Reviews

  • 26679002
  • Original Publications

  • 19648239,19666716,25918422