flavodoxin, binds FMN, replaces ferredoxin under conditions of iron limitation, probably involved in electron transfer to nitric oxide synthase
function
electron transfer
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.3|Electron transport/ other][SW|Categories] containing this gene/protein
[SW|electron transport/ other]This gene is a member of the following [SW|regulons]
[SW|Fur regulon], [SW|NsrR regulon], [SW|ResD regulon], [SW|Kre regulon]Gene
Coordinates on the chromosome (coding sequence)
1,487,038 -> 1,487,514
The protein
Protein family
flavodoxin-like domain (according to Swiss-Prot)Paralogous protein(s)
[protein|search|YkuP][SW|Cofactors]
FMN [Pubmed|25194416][SW|Interactions]
[protein|search|YkuN]-[protein|search|BioI] [Pubmed|15449930][protein|search|YjiB]-[protein|search|YkuN] [Pubmed|20186410][protein|search|Des]-[protein|search|YkuN] (electron transfer to [protein|search|Des]) [Pubmed|21665975][protein|search|YumC]-[protein|search|YkuN] (electron transfer from NADPH via [protein|search|YumC] to [protein|search|YkuN]) [Pubmed|25194416][protein|search|Nos]-[protein|search|YkuN] (electron transfer from to [protein|search|Nos]) [Pubmed|25194416][protein|search|QueE]-[protein|search|YkuN] (electron transfer) [Pubmed|25933252]Expression and Regulation
Operon
''[protein|search|ykuN]-[protein|search|ykuO]-[protein|search|ykuP]'' [Pubmed|12354229][SW|Sigma factor]
[protein|search|SigA] [Pubmed|12354229]Regulation
induced upon iron starvation ([protein|search|Fur]) [Pubmed|12354229]expressed under anaerobic conditions ([protein|search|ResD]) [Pubmed|24214949]induced by nitric oxide under anaerobic conditions ([protein|search|NsrR]) [Pubmed|24214949]Regulatory mechanism
[protein|search|Fur]: transcription repression [Pubmed|12354229][protein|search|ResD]: transcription activation [Pubmed|24214949][protein|search|NsrR]: transcription repression [Pubmed|24214949]Additional information
the ''[protein|search|ykuN]-[protein|search|ykuO]-[protein|search|ykuP]'' operon is strongly unregulated in a ''[SW|kre]'' mutant [Pubmed|26110430]References
15449930,17127770,12354229,20186410,24214949,21665975,25194416,25933252,26110430 
