SubtiBank SubtiBank
mciZ
Save the date! 20th International Conference on Bacilli and Gram-Positive Bacteria. Washington, D.C. July 23-26, 2019.

mciZ

[protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] inhibition peptide
locus
BSU_23616
pI
0.00
mw
4.00 kDa
function
inhibits GTPase activity of [protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] and Z ring formation during sporulation
product
[protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] inhibition peptide
essential
no
synonyms
S896

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]
  • Gene

    Coordinates
    2,459,114 → 2,459,288

    The protein

    Catalyzed reaction/ biological activity

  • inhibits GTPase activity of [protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ]and Z ring formation during [SW|sporulation]
  • Structure

  • [PDB|2MRW] [Pubmed|25848052]
  • [PDB|4U39] (the [protein|08EBBA57B807F8C27C37BEB275DF5E206935C698|MciZ]-[protein|41872E2EF00C79918DD077F2EF78F37E24FEB110|FtsZ] complex) [Pubmed|25848052]
  • Expression and Regulation

    Operons

    genes
    [gene|08EBBA57B807F8C27C37BEB275DF5E206935C698|mciZ]-[gene|B0897643562CDB25547223CCB9CFD0F9E78710E2|yqkF]
    description
    [pubmed|22383849]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [pubmed|18284588], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]
  • regulation

  • expressed early during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]) [Pubmed|18284588]
  • view in new tab

    References

    Reviews

  • 19680248
  • Original publications

  • 18284588,25848052,23237472,27752253,30636070