The second international online conference
#Subtillery2021 will be held 14th - 18th June - save the date, for more information see the
conference website!
The 21st
International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
yjiC
macrolide glycosyltransferase
function
synthesis of bacillaene
product
macrolide glycosyltransferase
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.14|Resistance against toxins/ antibiotics/ based on similarity]Gene
Coordinates
1,292,557 1,293,735
The protein
Protein family
UDP-glycosyltransferase family (with [protein|BD82663B1BF2763D2D2DE710C2896E4155419324|YdhE] and [protein|6D808BC20ADB6CA789288D50CA816D6BEE22CFC3|YojK], according to UniProt)Structure
[PDB|2IYA] (from Streptomyces antibioticus, 37% identity) [pubmed|17376874]Expression and Regulation
Operons
genes
[gene|D8E72C2523D5E6214C9CBAC2C1B27EA45378E162|yjiB]-[gene|02927D2CC9F44B99DB307DDFED2DD52DE2196120|yjiC]
description
[pubmed|22383849]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [pubmed|26577401], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]regulation
induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]) [pubmed|26577401]view in new tabBiological materials
Mutant
MGNA-A345 (yjiC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/345 NBRP B. subtilis, Japan]BKE12220 ([gene|02927D2CC9F44B99DB307DDFED2DD52DE2196120|yjiC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE12220 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAATCTCCAGTCTCCTT, downstream forward: _UP4_TAAAAACATAAAAACCGAAABKK12220 ([gene|02927D2CC9F44B99DB307DDFED2DD52DE2196120|yjiC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK12220 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGAATCTCCAGTCTCCTT, downstream forward: _UP4_TAAAAACATAAAAACCGAAAReferences
25354260,28315700,17376874,29338263,31726169,31786106