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dapA [2017-02-27 15:02:03]
dihydrodipicolinate synthase
function
biosynthesis of lysine and peptidoglycan
product
dihydrodipicolinate synthase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.6|Biosynthesis/ acquisition of lysine/ threonine][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]This gene is a member of the following [SW|regulons]
[SW|SigK regulon]Gene
Coordinates on the chromosome (coding sequence)
1,748,368 -> 1,749,240
Phenotypes of a mutant
essential [Pubmed|12682299]The protein
Catalyzed reaction/ biological activity
L-aspartate 4-semialdehyde pyruvate = L-2,3-dihydrodipicolinate 2 H2O (according to Swiss-Prot) Protein family
DHDPS family (according to Swiss-Prot)Structure
[PDB|3CPR] (from ''Corynebacterium glutamicum'', 39% identity, 58% similarity) [Pubmed|18930704][SW|Localization]
cytoplasm (according to Swiss-Prot)Expression and Regulation
[[this]]
References
