SubtiBank SubtiBank
yabD
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yabD

putative metal-dependent hydrolase
locus
BSU_00390
pI
4.81
mw
29.08 kDa
protein length
255 aa Sequence Blast
gene length
768 bp Sequence Blast
function
unknown
product
putative metal-dependent hydrolase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]
  • Gene

    Coordinates
    47,706 48,473

    The protein

    Protein family

  • [SW|Metallo-dependent hydrolases superfamily] (according to UniProt)
  • Structure

  • [PDB|2GZX] (from Staphylococcus aureus, 64% identity)
  • [SW|Localization]

  • cytoplasm (according to UniProt)
  • Expression and Regulation

    Operons

    genes
    [gene|DCBDD135F295B04FE7C7EB92E94638701CB320DD|metS]-[gene|00798BB5A769C464CC5FDDF7D9E41D30B473B9A8|yabD]
    description
    [Pubmed|22383849]

    regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: repression, [pubmed|14651647], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]
  • regulation

  • repressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]
  • additional information

  • term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of [gene|DCBDD135F295B04FE7C7EB92E94638701CB320DD|metS] [Pubmed|27120414]
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    Biological materials

    Mutant

  • MGNA-B904 (yabD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1903 NBRP B. subtilis, Japan]
  • BKE00390 ([gene|00798BB5A769C464CC5FDDF7D9E41D30B473B9A8|yabD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE00390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAGTGAAAAACTCCTTT, downstream forward: _UP4_TGACAAAAAACGCTAGCGGG
  • BKK00390 ([gene|00798BB5A769C464CC5FDDF7D9E41D30B473B9A8|yabD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK00390 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAAGTGAAAAACTCCTTT, downstream forward: _UP4_TGACAAAAAACGCTAGCGGG
  • References

  • 10747959