SubtiBank SubtiBank
ytxM
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ytxM

similar to prolyl aminopeptidase
Locus
BSU_30810
Isoelectric point
7.18
Molecular weight
30.55 kDa
Protein length
274 aa Sequence Blast
Gene length
825 bp Sequence Blast
Function
ubiquinone and menaquinone biosynthesis
Product
unknown
Essential
no
E.C.
4.2.99.20
Synonyms
ytfB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of menaquinone/ based on similarity

    • Gene

    Coordinates
    3,149,751 3,150,575

    The protein

    Catalyzed reaction/ biological activity

  • 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate --> (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate + pyruvate (according to UniProt)

    • Protein family

  • AB hydrolase superfamily (according to UniProt)

    • Domains

  • AB hydrolase-1 domain (aa 26-259) (according to UniProt)

    • Structure

  • 2XMZ (from Staphylococcus aureus, 34% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    menF-menD-ytxM-menB-menE-menC
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Additional information

  • A ncRNA is predicted between 'mntA' and 'menC' PubMed
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    Biological materials

    Mutant

  • MGNA-A283 (ytxM::erm), available at the NBRP B. subtilis, Japan
  • BKE30810 (ytxM::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GACACCATCTGATACCGTTA, downstream forward: _UP4_TGACTCATTCACATAGAGAA
  • BKK30810 (ytxM::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GACACCATCTGATACCGTTA, downstream forward: _UP4_TGACTCATTCACATAGAGAA

    • References

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