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yidC2

Sec-independent membrane protein translocase, required for development of genetic competence

Locus

BSU_23890

Isoelectric point

9.90

Molecular weight

30.60 kDa

Protein length

275 aa Sequence Blast

Gene length

828 bp Sequence Blast

Function

membrane insertion of proteins and protein secretion

Product

Sec-independent membrane protein translocase

Essential

Synonyms

yqjG,oxaAB

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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Categories containing this gene/protein

Information processing → Genetics → Genetic competence

Information processing → Protein synthesis, modification and degradation → Protein secretion

Lifestyles → Exponential and early post-exponential lifestyles → Genetic competence

Groups of genes → Membrane proteins

Gene

Coordinates

2,483,904 2,484,731

The protein

Protein family

OXA1/ALB3/YidC family (with YidC1, according to UniProt) PubMed

Paralogous protein(s)

YidC1:

Structure

3WO6 (from Bacillus halodurans, 41% identity) PubMed

Localization

membrane PubMed

Expression and Regulation

Operons

Genes

mifM-yidC2

Description

PubMed

Regulatory mechanism

MifM: attenuation, an mRNA hairpin of the yqjG transcript unfold upon translation arrest of MifM at decreased YidC1 levels, in MifM regulon

Regulation

repressed by large amounts of SpoIIIJ, induced by small amounts of SpoIIIJ (MifM) PubMed

Additional information

An [ncRNA|search|antisense RNA] is predicted for 'mifM' PubMed

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Biological materials

Mutant

MGNA-C389 (yqjG::erm), available at the NBRP B. subtilis, Japan

BKE23890 (yidC2::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAATTTTGTTCTCCTCCTTT, downstream forward: _UP4_TAAAAAAGCAACCCCGTGCA

BKK23890 (yidC2::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAATTTTGTTCTCCTCCTTT, downstream forward: _UP4_TAAAAAAGCAACCCCGTGCA

References

Reviews

Original publications