SubtiBank SubtiBank
yhcA
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

yhcA

c-di-AMP exporter
Locus
BSU_09010
Isoelectric point
9.49
Molecular weight
58.17 kDa
Protein length
532 aa Sequence Blast
Gene length
1599 bp Sequence Blast
Function
secretion of cyclic di-AMP
Product
c-di-AMP exporter
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
Loading

Categories containing this gene/protein

  • Cellular processes → Transporters → Transporters/ other → Other exporters
  • Metabolism → Nucleotide metabolism → Metabolism of signalling nucleotides
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    977,775 979,373

    The protein

    Catalyzed reaction/ biological activity

  • secretion of cyclic di-AMP PubMed

    • Protein family

  • major facilitator superfamily (according to UniProt)
  • EmrB family (according to UniProt)

    • Paralogous protein(s)

  • YcnB, LmrB

    • Structure

  • 6E8J (from Hyphomonas neptunium, corresponds to aa 93 ... 204, 28% identity)

    • Localization

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    yhbI-yhbJ-yhcA-yhcB-yhcC
    Description
    PubMed

    Additional information

  • the mRNA is substantially stabilized upon depletion of RNase Y (the half-life of the mRNA increases from 4 to 41 min) PubMed
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B471 (yhcA::erm), available at the NBRP B. subtilis, Japan
  • GP1704 (yhcA::ermC, without terminator), available in Jörg Stülke's lab
  • BKE09010 (yhcA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTAAGACAACCTCCTTT, downstream forward: _UP4_TAATCTGTACAGGGAGGTTT
  • BKK09010 (yhcA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTAAGACAACCTCCTTT, downstream forward: _UP4_TAATCTGTACAGGGAGGTTT

    • References

    Loading