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swrB
control of [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD] activity, required for full [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD] activity, activates the flagellar type III secretion export apparatus by the membrane protein [protein|6ED6C3DDC4F3142FD01D32840D955B7E4A19F385|FliP]
function
control of [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD] activity
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.5|Additional chemotaxis signal transduction and regulatory proteins][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
1,717,286 1,717,789
Phenotypes of a mutant
no swarming motility on B medium [Pubmed|19202088]defective in the assembly of the flagellar hook [Pubmed|26244495]The protein
[SW|Localization]
membrane-proximal (Spotty) [Pubmed|16479537]membrane [Pubmed|26244495]Biological materials
Mutant
MGNA-B082 (ylxL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1081 NBRP B. subtilis, Japan]BKE16480 ([gene|347ACF1D4E2D0C1B4E9DF0DEA9807A6A7D1519AC|swrB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTTCACTCGCTAAC, downstream forward: _UP4_TGATTGTCGGATAAAGCTGTBKK16480 ([gene|347ACF1D4E2D0C1B4E9DF0DEA9807A6A7D1519AC|swrB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTTTCACTCGCTAAC, downstream forward: _UP4_TGATTGTCGGATAAAGCTGTReferences
15175317,19202088,16357223,15066026,9335309,14651647,16479537,19202088,9657996,8157612,17850253,24386445,22329926,26244495